The first comprehensive textbook to cover the entire RNA biology field, from nuclear processing to export, editing, splicing, translation, localisation and stability, RNA interference and non-coding RNAs. Read more and order...
I am interested in RNA biology, a growing area of research that includes RNA processing; alternative splicing; mRNA export, translation and localisation; mRNA stability; RNA interference and microRNAs.
The focus of my research group is on alternative splicing. Alternative splicing is the main process through which genes can express multiple protein isoforms. Over two thirds of human genes are alternatively spliced and it is estimated that 15% of all disease-associated mutations in humans affect alternative splicing.
Current projects
- Role of the SR protein kinase SRPK1 in cancer
- Alternative splicing of VEGF, HER2, H-Ras, IR, ERG and rhCG
- The tumour suppressor gene WT1 in development and disease
- The novel mRNA and P-body associated protein RAP55
- The stress-induced Arabidopsis mRNA-binding proteins atGRP7/8
- Textbook: The Molecular Biology of RNA. Elliott and Ladomery. Due for publication in December 2010, Oxford University Press.
Latest 5 research papers
Click on the title to view the abstract.
Interested in a self-funded PhD studentship?
From time to time, depending on grants, PhD studentships are available in my lab. However I am also happy to consider a self-funded (or part self-funded) PhD studentship at any time. Read more about the self-funded PhD studentship.
